Titanium is known to be a non-allergic material. However many studies show cases of metal allergy caused by titanium containing materials. Two-hundred random volunteers were taken as a study sample between the age group of 18-60 years and described after patch test was done. Observation showed allergic symptoms in about 4% of the subject population. Discussion: Applications such as plastic surgery, dental implants, white pigments etc. Titanium is used in the form of titanium dioxide which leads to rapid expansion of titanium containing products. This rapid expansion of titanium containing products leads to increase in percutaneous and premucosal exposure of titanium in the population. Conclusion: Risk of titanium containing material leading to allergy is lesser than that of other metal material. Therefore during implant placement patient should be asked regarding medical history of hypersensitivity reactions to metals and patch testing should be done.
