Myoepithelial soft tissue tumors often pose diagnostic challenges due to their rarity. Their identification relies primarily on pathological analysis, although clinical and radiological features can guide the healthcare professional. Myoepithelial tumors, when benign, generally do not invade bone. In this context, we present a new case of this rare pathology, observed in the soft tissues of the thigh of a 32-year-old individual, with no bone involvement detected. Surgery was completely successful, and after one year, the patient showed a favorable evolution, with no signs of local recurrence. It should be noted that myoepitheliomas mainly affect the extremities. When they are deep-seated, it is essential to distinguish them from extraskeletal myxoid chondrosarcomas, parachordomas and synovialosarcomas. The majority of myoepitheliomas are benign in nature, although metastasis is a possibility.
