Madura tribe is one of the tribes that have the character as a formidable fighter, hard worker, and has a strong Islamic religious culture. So that requires a good approach to overcome the problem of stunting. Stunting is a chronic malnutrition condition that causes growth disturbance in children. The purpose of this study was to analyze the influence of cultural factors, social structure and child factors on stunting prevention which is moderated by family independence. The study design was observational with a cross sectional approach. Exogenous variables are cultural factors, while endogenous variables are: 1) family health independence, 2) stunting prevention and 3) stunting events. The number of research samples are 230 families. Sampling technique using cluster random sampling method. The instrument uses a questionnaire. Statistical tests using partial least square (PLS) structural model testing with α> 1.96. The results of the partial least squares test indicate that the construct variables are cultural factors and social structure, family independence and stunting prevention (T> 1.96). All exogenous variables had a significant influence on the incidence of stunting except maternal, educational and child factors (statistic T <1.96). Finding: family independence in stunting prevention can be formed through social and cultural structural factors.
