Objective: To demonstrate the role of intranasal steroid in the prevention of adenoid regrowth after adenoidectomy. Methods: Prospective randomized controlled study. One hundred children after adenoidectomy were divided into 2 groups. Group I received postoperative intranasal steroid and group II received postoperative intranasal saline spray. Both medications were administered for 12 weeks postoperatively. Patients were followed up for 6 months. Results: Significant difference between both groups after 6 weeks and after 6 months.The intranasal steroid group had significantly lower score after 6 months as regards nasal obstruction, nasal discharge, and snoring than the intranasal saline group. As regards lateral radiographs, there was statistically significant difference between both groups 6 months postoperatively. Conclusion: Factors influencing the outcome of intranasal steroids therapy in the prevention of adenoid regrowth have not been identified. However, this treatment may obtain successful results in children to avoid readenoidectomy.