The Hyderabad Karnataka (HK) is most backward region with a rich tradition of folk medicinal treatment, which is rooted in the masses of this region since time immemorial and such kind of tradition, is still practiced in different strata of groups of the region. Total 361 practitioners are identified and interviewed for the study. According to the study male practitioners are dominated and the majority of folk medicine practitioners is illiterates. Most of the practitioners practice medicinal treatment as part-time basis and found almost practitioners are in aged group with well knowledge experience in their folk medicine practice. Practitioners provide treatment for all kinds of illness and treatment is more or less social service to the society in this region.