The work x-rays the current efforts made by government to promote industrialization, micro, small & medium scale enterprises (MSMEs), and foster local and foreign direct investments (FDI) in Nigeria. Programmes such as NIRP, NEDEP, NISDP and NCCN have been introduced to establish Nigeria in four key areas of Industry, Trade, Investment, and MSME development. The work further highlights on bilateral negotiations, both past and present, and the rejection of the controversial ECOWAS – EU Economic Partnership Agreement (EPA), aimed at increasing global markets for locally-produced goods and encouraging local production respectively. The findings obtained affirm the conscious efforts being made by the present administration to foster industrialization and job creation. These efforts, when sustained and complemented with positive activities of other stakeholders, especially the organized private sector (OPS), would be key towards achieving sustainable development of the nation’s industrial sector and global market share.